Adrafinil
What Is Adrafinil?
Adrafinil is a eugeroic compound and prodrug to modafinil. It promotes wakefulness and alertness without the jittery effects of traditional stimulants. Metabolized in the liver to modafinil, it offers similar cognitive benefits.
Adrafinil Research & Studies
01 Behavioral Activating Effects of Adrafinil in Aged Canines ▸
Study demonstrates that adrafinil increases locomotor activity and directed sniffing in aged dogs, with variable individual responses.
View Study (ScienceDirect)02 Identification of adrafinil and its main metabolite modafinil in human hair ▸
Research shows adrafinil and modafinil can be detected in human hair following single consumption, helping distinguish trafficking cases from self-use.
View Study (Oxford Academic)03 Adrafinil disrupts performance on a delayed nonmatching-to-position task in aged beagle dogs ▸
Study reveals adrafinil significantly impairs working memory in aged dogs, potentially via increased noradrenergic transmission in prefrontal cortex.
View Study (ScienceDirect)04 Adrafinil: Effects on behavior and cognition in aged canines ▸
Research characterizes adrafinil as a behavioral stimulant with cognitive enhancement potential in aged dogs, though mechanisms remain unclear.
View Study (ScienceDirect)05 Oral Administration of Adrafinil Improves Discrimination Learning in Aged Beagle Dogs ▸
Investigation demonstrates adrafinil significantly enhances discrimination learning in aged dogs, possibly through enhanced vigilance and motivation.
View Study (ScienceDirect)06 Fluorescent zinc and copper complexes for detection of adrafinil ▸
Fluorescent complexes provide detection method for adrafinil in paper-based microfluidic devices, useful for identifying banned performance-enhancing substances.
View Study (Royal Society of Chemistry)07 Thermal degradation of modafinil analogs in GC injector ▸
Analysis shows thermal degradation of modafinil and adrafinil compounds in gas chromatography injectors can produce unexpected byproducts.
View Study (Analytical Science Journals)08 Comparison of the effects of adrafinil, propentofylline, and nicergoline on behavior in aged dogs ▸
Research indicates adrafinil treatment may improve quality of life in aged dogs by increasing exploratory behavior and alertness.
View Study (AVMA Publications)09 Development and Validation of an Analytical Method to Identify Novel Modafinil Analogs ▸
LC-HRMS method effectively identifies and quantifies novel modafinil analogs in dietary supplements, protecting consumers from undisclosed active ingredients.
View Study (Taylor and Francis Online)Adrafinil User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users appreciate its wakefulness-promoting effects, though many prefer modafinil directly due to concerns about liver metabolism.
Adrafinil Benefits, Dosage & Side Effects
- Increased Wakefulness: Users report sustained alertness and reduced fatigue without the crash associated with caffeine.
- Cognitive Enhancement: Some users note improved focus and mental clarity during tasks.
- Gradual Onset: Effects typically begin 60-90 minutes after ingestion due to liver conversion.
- Individual Variation: Response varies based on liver enzyme activity and metabolism.
- Tolerance Development: Some users report diminishing effects with regular use.
- Typical Range: 300-600mg per day, usually taken in the morning.
- Avoid Daily Use: Due to liver metabolism concerns, many cycle usage or use intermittently.
- Liver Strain: Long-term use may stress the liver; liver function monitoring is recommended.
- Headaches: Some users report headaches, often mitigated by staying hydrated.
- Insomnia: Taking too late in the day can disrupt sleep.
- Unscheduled: Legal in most countries without prescription.
- Online Vendors: Available from various nootropic suppliers.
Community Reviews
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