L-Theanine

What Is L-Theanine?

SupplementNootropic

L-Theanine is an amino acid found primarily in tea leaves that promotes relaxation without sedation. It increases alpha brain waves, enhances focus when combined with caffeine, and supports calm, clear-headed mental states.

L-Theanine Research & Studies

01 l-Theanine: An astounding sui generis integrant in tea

L-theanine offers potential health benefits including anti-stress and neuroprotective effects with modulation of anti-neoplastic agents.

View Study (ScienceDirect)
02 L-Theanine and Immunity: A Review

L-theanine enhances immune function, reduces immunosuppression, and serves as an immunomodulator for inflammation management.

View Study (MDPI)
03 l-Theanine Activates the Browning of White Adipose Tissue Through the AMPK Axis and Ameliorates Diet-Induced Obesity

L-theanine triggers white adipose tissue browning and reduces diet-induced obesity by enhancing thermogenesis.

View Study (American Diabetes Association)
04 l-Theanine reduces psychological and physiological stress responses

L-theanine intake decreases stress responses through inhibition of cortical neuron excitation during acute stress.

View Study (ScienceDirect)
05 L-theanine: an astounding sui generis amino acid in poultry nutrition

L-theanine demonstrates antioxidant, growth-promoting, immune-boosting, and anti-stress benefits in poultry applications.

View Study (ScienceDirect)
06 L-theanine relieves symptoms in patients with schizophrenia: an 8-week, randomized, double-blind study

L-theanine augmentation of antipsychotic therapy improves positive, activation, and anxiety symptoms in schizophrenia.

View Study (Journal of Clinical Psychiatry)
07 l-Theanine regulates glucose, lipid, and protein metabolism via insulin and AMP-activated protein kinase signaling

L-theanine regulates metabolism in rats through insulin and AMPK signaling mechanisms.

View Study (Royal Society of Chemistry)
08 Psychotropic effects of L-theanine and its clinical properties

L-theanine demonstrates promising therapeutic potential for managing anxiety disorders and stress.

View Study (ScienceDirect)
09 L-theanine in the adjunctive treatment of generalized anxiety disorder

L-theanine showed limited efficacy for anxiety reduction but may improve sleep satisfaction in those with insomnia symptoms.

View Study (ScienceDirect)
10 An overview of biological production of L-theanine

Bacterial enzymes demonstrate potential for producing L-theanine for human health and food applications.

View Study (ScienceDirect)

L-Theanine User Reviews & Experiences

82% Positive

*Based on large scale analysis of publicly available user experiences

Widely praised for its calming effects without drowsiness. The combination with caffeine is a popular starting nootropic stack. Very well-tolerated with minimal side effects.

L-Theanine Benefits, Dosage & Side Effects

Effects
  • Relaxation Without Sedation: Promotes calm without drowsiness.
  • Focus Enhancement: Especially effective combined with caffeine.
  • Anxiety Reduction: Helps reduce stress and anxiety.
  • Sleep Support: Can improve sleep quality when taken before bed.
  • Alpha Waves: Increases relaxed, alert brain state.
Effectiveness
  • Caffeine Synergy: Most popular use is with caffeine for focused energy.
  • Fast Acting: Effects typically felt within 30-60 minutes.
  • Consistent Results: Reliably produces calming effects.
Dosage & Administration
  • Typical Range: 100-400mg daily.
  • With Caffeine: Common ratio is 2:1 (L-theanine:caffeine).
  • For Sleep: 200-400mg 30-60 minutes before bed.
Side Effects
  • Extremely Safe: Very few side effects reported.
  • Possible Drowsiness: At high doses, some may feel sleepy.
  • Lower Blood Pressure: May slightly reduce blood pressure.
  • Drug Interactions: Minimal; generally safe with most substances.
Availability & Sourcing
  • Widely Available: Found in almost all supplement stores.
  • Very Affordable: One of the most cost-effective nootropics.
  • Multiple Forms: Capsules, powder, and in many pre-made stacks.

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