Melanotan 2

What Is Melanotan 2?

Peptide

Melanotan 2 is a synthetic peptide that stimulates melanin production for tanning, increases libido, and may suppress appetite. It acts on melanocortin receptors and produces faster, more pronounced effects than MT-1.

Melanotan 2 Research & Studies

01 Melanotan II: a possible cause of renal infarction: review of the literature and case report

Examines renal infarction as a rare complication potentially induced by Melanotan II, reviewing mechanisms including blood clot formation.

View Study (PubMed)
02 Melanotan-II reverses memory impairment induced by a short-term HF diet

Demonstrates that Melanotan-II reversed negative neurobehavioral effects caused by high-fat diet in zebrafish models.

View Study (ScienceDirect)
03 Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food

Found that melanotan-II injection reduced food intake motivation in mice without causing adverse effects.

View Study (ScienceDirect)
04 The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat

Tested melanotan-II for nerve recovery in rats, finding significant sensory function improvement and cisplatin toxicity protection.

View Study (ScienceDirect)
05 The protective effects of the melanocortin receptor agonist, melanotan-II, against binge-like ethanol drinking are facilitated by deletion of the MC3 receptor in mice

Found melanotan-II successfully reduces binge alcohol consumption through specific receptor mechanisms.

View Study (ScienceDirect)

Melanotan 2 User Reviews & Experiences

62% Mixed

*Based on large scale analysis of publicly available user experiences

Popular for tanning and libido effects. Users report fast results but more side effects than MT-1. Concerns about mole changes and long-term safety exist.

Melanotan 2 Benefits, Dosage & Side Effects

Effects
  • Rapid Tanning: Faster skin darkening than MT-1.
  • Increased Libido: Strong aphrodisiac effects, especially in men.
  • Appetite Suppression: Many users report reduced hunger.
  • Spontaneous Erections: Common side effect in men.
Effectiveness
  • Fast Acting: Visible tanning within days to weeks.
  • Potent Libido Effects: Very noticeable sexual enhancement.
  • Variable Tanning: Results depend on baseline skin tone.
Dosage & Administration
  • Starting Dose: 0.25mg to assess tolerance.
  • Typical Range: 0.5-1mg per injection.
  • Loading/Maintenance: Higher frequency initially, then reduced.
Side Effects
  • Nausea: Very common, especially initially.
  • Flushing: Facial flushing after injection.
  • Mole Changes: Darkening and potential changes to moles.
  • Spontaneous Erections: Can be inconvenient.
  • Blood Pressure: May affect cardiovascular system.
Availability & Sourcing
  • Research Chemical: Available from peptide suppliers.
  • Not Approved: Not FDA approved for any indication.
  • Widely Used: Popular despite safety concerns.

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