Noopept
What Is Noopept?
Noopept is a potent synthetic nootropic developed in Russia, approximately 1000x more potent than piracetam by weight. It enhances memory, learning, and provides neuroprotective effects through BDNF and NGF modulation.
Noopept Research & Studies
01 Noopept in the treatment of mild cognitive impairment in patients with stroke ▸
Study of 60 stroke patients treated with noopept 20 mg daily for 12 months showed significant cognitive improvements after 2 months.
View Study (PubMed)02 Clinical and electroencephalographic characteristic of noopept in patients with mild cognitive impairment ▸
Research examined noopept's impact on brain activity, finding increased alpha- and beta-rhythm power while reducing delta-rhythm power.
View Study (PubMed)03 Effect of nootropic dipeptide noopept on CA1 pyramidal neurons involves α7AChRs ▸
Noopept enhances hippocampal neuron activity by boosting inhibitory interneuron firing through nicotinic acetylcholine receptors.
View Study (ScienceDirect)04 Effects of noopept on cognitive functions and pubertal process in rats with diabetes ▸
Noopept normalized delayed puberty and reduced blood glucose levels in diabetic rats, improving insulin resistance markers.
View Study (ScienceDirect)05 QbD-driven development of dissolving microneedle patch loaded with ultradeformable liposomes encapsulated Noopept ▸
Development of transdermal microneedle delivery system for noopept showed enhanced bioavailability and skin penetration.
View Study (ScienceDirect)06 Neuroprotective and Nootropic Drug Noopept Rescues α-Synuclein Amyloid Cytotoxicity ▸
Noopept mitigates harmful effects of α-synuclein linked to Parkinson's disease by promoting safer aggregation forms.
View Study (ScienceDirect)07 Novel nootropic dipeptide Noopept increases inhibitory synaptic transmission in CA1 pyramidal cells ▸
Research found noopept increases inhibitory signal frequency in hippocampal brain cells through activation of specific inhibitory neurons.
View Study (ScienceDirect)08 Noopept stimulates the expression of NGF and BDNF in rat hippocampus ▸
Noopept increases neurotrophic factor expression in the hippocampus, potentially enhancing cognitive functions.
View Study (PubMed)Noopept User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users appreciate its potency and cognitive benefits. Some report anxiety reduction while others experience increased stimulation. Individual response varies significantly.
Noopept Benefits, Dosage & Side Effects
- Memory Enhancement: Improved recall and memory formation.
- Mental Clarity: Enhanced focus and clear thinking.
- Neuroprotection: May protect against cognitive decline.
- Mood Effects: Some report anxiolytic effects; others stimulation.
- BDNF/NGF Increase: Upregulates neurotrophic factors.
- Highly Potent: Active at very low doses (10-30mg).
- Fast Onset: Effects often felt within an hour.
- Individual Variation: Response can be stimulating or calming.
- Typical Range: 10-30mg daily, often divided into 2-3 doses.
- Sublingual: Can be taken sublingually for faster onset.
- Cycling: Some cycle to maintain sensitivity.
- Irritability: Some users report increased irritability.
- Brain Fog: Paradoxically, some experience this at wrong doses.
- Headaches: Possible, often from inadequate choline.
- Generally Well Tolerated: Most users have minimal issues.
- Research Chemical: Available from nootropic vendors.
- Legal Status: Unscheduled in most countries.
- Affordable: Very cost-effective due to low dosing.
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