PROSTATILEN
What Is PROSTATILEN?
Prostatilen is a polypeptide bioregulatory preparation extracted from bovine prostate tissue that has been used primarily in Eastern European countries since the 1990s. It works by exerting organotropic effects on prostate tissue, demonstrating anti-inflammatory, immunomodulatory, and microcirculation-enhancing properties. The supplement is primarily used to treat chronic prostatitis, benign prostatic hyperplasia (BPH), male infertility due to impaired spermatogenesis, and urinary dysfunction.
PROSTATILEN Research & Studies
01 Influence of Adding Zinc Arginyle-Glycinate to Improve Efficacy of Bioregulatory Peptides of the Prostate Gland in Treatment of Patients with Impaired Sperm Parameters ▸
A newer formulation of Prostatilen containing added zinc arginyle-glycinate (Prostatilen AC) showed enhanced positive effects on spermatogenesis parameters in men aged 25-45 with chronic abacterial prostatitis and reproductive dysfunction.
View Study (PubMed)02 Effect of Prostatilen AC Suppositories on Course of Experimental Prostatitis ▸
In rat models of chronic prostatitis, Prostatilen AC demonstrated pronounced anti-inflammatory effects, reduced prostate weight and inflammatory markers, normalized urination, increased diuresis, and elevated testosterone levels while showing antioxidant properties.
View Study (PubMed)03 The Use of Prostatilen in Treating Patients with Prostatic Diseases ▸
Clinical trials in 52 patients with chronic prostatitis and prostatic adenoma showed Prostatilen reduced pain and urinary symptoms, improved sexual function and spermatogenesis, increased uroflowmetric indices, and demonstrated antibacterial and immunomodulation effects without adverse reactions.
View Study (PubMed)04 Our Experience in the Use of Prostatilen in Urology ▸
In 1,115 patients with chronic pyelonephritis and prostatitis, Prostatilen showed corrective effects on hemocoagulation and immunity disorders, restored microcirculation, and suppressed inflammation in the kidney and prostate.
View Study (PubMed)05 The Effect of Prostatilen on the Hemostatic Indices in Chronic Prostatitis ▸
Clinical and experimental studies demonstrated that Prostatilen normalizes hemostatic parameters in chronic prostatitis by inhibiting hypercoagulation, normalizing platelet function, and activating fibrinolysis, suggesting this contributes to its therapeutic efficacy.
View Study (PubMed)06 Prooxidant-Antioxidant Balance in the Prostate and Blood of Rats with Sulpyride-Induced Prostatic Hyperplasia Corrected with Prostatilen ▸
In rats with drug-induced prostatic hyperplasia, 30-day treatment with Prostatilen prevented the development of hyperplasia and normalized the prooxidant-antioxidant balance in prostate tissue and blood.
View Study (PubMed)07 The Use of Prostatilen in Treating Patients with Chronic Prostatitis ▸
In 307 patients with chronic prostatitis, Prostatilen administered at 5-10 mg intramuscularly for 5-10 days showed clinical improvement after 2-3 injections with 96.7% of patients experiencing symptom relief, positive laboratory changes, and improved urodynamic parameters.
View Study (PubMed)08 The Validation of the Use of Prostatilen and Testilin for Treating Male Infertility ▸
Experimental studies in male rats showed that Prostatilen exerts a stimulating effect on spermatogenesis and androgenic testicular functions, correcting androgenic-estrogenic balance and potentially benefiting male infertility and hypoandrogenization.
View Study (PubMed)PROSTATILEN User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Limited Reddit discussions about Prostatilen. This peptide is primarily used in Eastern European countries and has minimal visibility in English-speaking nootropic communities.
PROSTATILEN Benefits, Dosage & Side Effects
- Anti-inflammatory Action: Reduces prostatic inflammation, lowers inflammatory markers including C-reactive protein and ceruloplasmin, and decreases leukocyte count in prostatic secretions
- Improved Urinary Function: Enhances urination parameters, increases uroflowmetric indices, reduces residual urine volume, and stimulates smooth muscle contractility of the urinary bladder
- Enhanced Sexual and Reproductive Function: Improves copulative function, stimulates spermatogenesis, increases sperm parameters, and may elevate testosterone levels
- Immunomodulation and Microcirculation: Corrects immunity disorders by normalizing T-lymphocyte counts and function, restores microcirculation, and normalizes hemocoagulation by reducing hypercoagulation and activating fibrinolysis
- Rapid Onset: Clinical effects typically manifest after 2-3 injections with maximal benefits achieved after 5-6 injections in chronic prostatitis treatment
- High Response Rate: Studies report 96.7% of chronic prostatitis patients experiencing symptom disappearance or attenuation with Prostatilen treatment
- Multi-organ Benefits: Beyond prostate effects, demonstrates efficacy in treating chronic pyelonephritis and shows antibacterial properties alongside tissue-specific actions
- Enhanced Formulation: The addition of zinc arginyle-glycinate to create Prostatilen AC appears to improve efficacy particularly for spermatogenesis and reproductive dysfunction parameters
- Standard Injectable Dose: 5-10 mg administered intramuscularly once daily for 5-10 days is the most commonly studied regimen for chronic prostatitis
- Rectal Suppository Form: 30 mg suppositories containing dimexide have been studied and found effective for benign prostatic hyperplasia symptoms
- Treatment Duration: Typical courses range from 5-10 days, with clinical effects appearing after 2-3 days and maximal benefits by day 5-6
- Enhanced Formula: Prostatilen AC suppositories combine bioregulatory peptides with zinc arginyle-glycinate dihydrochloride for enhanced reproductive benefits
- Minimal Adverse Effects: Clinical studies consistently report absence of adverse reactions or side effects with standard dosing protocols
- Mutagenicity Concerns: One study found that 5 microgram doses induced chromosomal aberrations in mice, though lower doses (2.5 micrograms) showed no significant mutagenic effects
- Immobilization Safety: Immobilizing Prostatilen in polyvinyl alcohol was shown to reduce mutagenic potential in experimental models
- Generally Well-Tolerated: Across multiple clinical trials involving over 1,400 patients, the supplement demonstrated good tolerability with therapeutic benefits outweighing risks
- Regional Availability: Prostatilen appears to be primarily available and studied in Eastern European countries, particularly Russia and Ukraine, with limited presence in Western markets
- Prescription Status: Clinical literature indicates it has been used as a registered pharmaceutical preparation requiring medical supervision, typically administered via injection or suppository in clinical settings
- Formulation Variants: Available in multiple forms including injectable solutions (5-10 mg), rectal suppositories (30 mg), and the enhanced Prostatilen AC formulation containing additional zinc compounds
Community Reviews
Share your experience with PROSTATILEN and help others make informed decisions.
Write a Review
Sign in to leave a review