PT-141
What Is PT-141?
PT-141 (Bremelanotide) is an FDA-approved peptide for treating hypoactive sexual desire disorder. It works through melanocortin receptors in the brain to increase sexual desire, making it unique among sexual health treatments.
PT-141 Research & Studies
01 Effect of bremelanotide on body weight of obese women ▸
Bremelanotide reduced body weight and caloric intake in obese women in clinical trials, showing promise as a treatment for weight loss.
View Study (Diabetes Obesity and Metabolism)02 Long-term safety and efficacy of bremelanotide for Hypoactive Sexual Desire Disorder ▸
Study found that bremelanotide effectively improved sexual desire in premenopausal women with hypoactive sexual desire disorder over 52 weeks.
View Study (George Washington University)03 Bremelanotide for the treatment of Hypoactive Sexual Desire Disorder ▸
In clinical trials, Bremelanotide significantly increased sexual desire and reduced distress in women with sexual dysfunction, showing a favorable safety profile.
View Study (MacDonald Women's Hospital)PT-141 User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users report significant increases in libido and sexual desire. Effects work differently than PDE5 inhibitors - targets desire rather than mechanics. Nausea common but manageable.
PT-141 Benefits, Dosage & Side Effects
- Increased Libido: Enhanced sexual desire in both men and women.
- Arousal Enhancement: Improved ability to become aroused.
- Works Centrally: Acts on brain rather than blood vessels.
- Effective for Both Sexes: Benefits men and women.
- FDA Approved: Clinically validated efficacy.
- Different Mechanism: Works when PDE5 inhibitors don't.
- Psychological Desire: Enhances wanting, not just function.
- Standard Dose: 1.75mg subcutaneously as needed.
- Timing: Administered 45 minutes before sexual activity.
- Frequency: Not more than once in 24 hours.
- Nausea: Very common, can be significant.
- Flushing: Facial redness and warmth.
- Blood Pressure: Transient increase possible.
- Headache: Occasionally reported.
- FDA Approved: Available as Vyleesi by prescription.
- Research Chemical: Also available from peptide suppliers.
- Higher Cost: Branded version is expensive.
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